General Pharmacy Experiments
Preparation of Peppermint-Water
Measure accurately 10 mL of Peppermint oil with the help of a pipette and transfer it into a measuring flask containing about 300 mL of purified water. Shake this mixture vigorously for 5 min either manually or with the help of magnetic stirrer. Make sure that all the droplets of peppermint oil are uniformly distributed in the water. Finally, make up the volume to 1000 mL with purified water and shake well for 2 min. The product thus obtained is called as peppermint-water.
Preparation of Concentrated Anise-Water
Measure 20 mL of anise oil by pipette and dissolve it into 700 mL of 90% ethanol in a measuring flask. Thereafter, make up the volume to 1000 mL by adding purified water. Preserve the preparation in air tight and light-resistant container and store it in a cool place.
Preparation of Simple Syrup
There are two methods given in pharmacopoeias to prepare simple syrup. According to Indian Pharmacopoeia, weight accurately 66.7 g of sucrose and transfer it into a beaker containing 33.3 g of purified water and heat it until the sucrose is dissolved completely. On the other hand, according to United State Pharmacopoeia, weight accurately 85 g of sucrose and transfer it into a beaker and make the volume up to 100 mL by adding purified water. Thereafter, stir the mixture until the whole amount of sucrose is dissolved in water.
Preparation of Orange Syrup
Prepare fresh orange tincture using a simple percolation method in which fresh cut lemon pieces are used. Measure 60 mL of orange tincture and mix it in 940 mL of simple syrup with continuous stirring. The product thus obtained is called as orange syrup.
Preparation of Lemon Syrup
Dissolve 25 g of citric acid monohydrate in a little amount of simple syrup. To it, add 5 mL of lemon spirit and shake vigorously. Thereafter, make the volume up to 1000 mL by adding simple syrup. The product thus obtained is called as lemon syrup.
Preparation of Jelly Base
Weight 7 g of sodium alginate with 7 g of glycerol in a glass mortar. Dissolve 0.2 g of methyl hydroxyl benzoate and 0.05 g of calcium gluconate in about 80 mL of purified water with the aid of heat. Cool it to about 60 °C and stir rapidly with a high-speed stirrer. Add the sodium alginate-glycerol mixture gently to the vortex and continue stirring until the dispersion is homogeneous. Adjust the weight up to 100 g by adding hot purified water with continuous stirring.
Preparation of Lubricating Jelly
Dissolve 100 mg methyl hydroxyl benzoate in 80 mL of purified water using heat. Cool and transfer 40 mL of the solution to a beaker. Warm it to about 70 °C and stir vigorously with an electric stirrer. Mix 5 g of medium viscosity grade Sodium Carboxymethyl cellulose with 15 g of glycerine in a glass mortar and gently pour the mixture into the vortex. Stir until a clear gel is formed. Then, add 0.1 mg patent blue V dye by obtaining it with dilution method, adjust weight up to 100 g by adding hot purified water and stir until it gets cold.
Preparation of Glycero-Gelatin Jelly
Prepare jelly base using 15 g of gelatine, 35 g of glycerol and 30 mL purified water, heat at 100 °C for 1 h. Weight 15 g of zinc oxide, after shifting through a No. 180 sieve, and add a small amount to the molten base, stir gently to avoid excessive incorporation of air. Adjust weight up to 100 g by adding hot purified water. Continuously stirring until the preparation is viscous enough to hold the powder in suspension but should not be too thick to pour.
Preparation of Carbomer Jelly
Dissolve 1 g of ephedrine sulphate in 95 mL of water, cool the solution if necessary, and slowly add 2 g of Carbomer with vigorous mechanical stirring. Continue mixing until a cloudy, lump-free dispersion is obtained. Allow it to stand for separating air bubbles. Add 1.65 mL of triethanolamine, a drop at a time, stir gently with a plastic spatula to avoid entrapping air. Incorporate the remaining water to adjust the weight to 100 g.