In the actual Covid-19 emergency, as pandemic disease, in many countries at the same time, there was the rapid need to use preventive and therapeutic measures to control the diffusion of infection. In PC Area (Italy North) during the period between March and May 2020, there were observed about 1000 deaths related to Covid-19 (in March 2020 271% death vs 2019). Between all the measures submitted by a public international institution like WHO, OMS, CDC and many others, the deeply use of disinfectants product became a crucial fact in safety procedure and protocols. The high amount of these disinfectants and antiseptic was needed especially in hospital settings or assimilates structure (named as the Covid-19 hospital) but also for territorial healthcare need. So, it was needed to buy these products from industries but also to start an internal production in Galenic Laboratories. This was because of pharmaceutical industries were not provided, in some cases, the requested amount of these safe life products. In this work, we reported a practical experience in a public hospital, PC area related galenic extra-ordinary production of disinfectants and antiseptics. The result of this local experience can be easily translated to other advanced and developing countries in the world.