The book Śafaśifa Enna Viṣacikilsa, central to the present study, is a traditional medical treatise written in the Arabi-Malayalam literary dialect by 19th-century author Konaganamveettil Ibrahimkutty Musliyar. This concise yet comprehensive text addresses all aspects of poisoning as understood in 19th-century Kerala. It draws from a rich blend of toxicological knowledge found in Ayurvedic, Arabic, and local Kerala texts up to the 19th century CE. The book categorizes various types of poisoning and integrates both physical and metaphysical approaches. While certain sections reflect clear parallels to Ayurvedic practices, others present unique perspectives that diverge from conventional Ayurvedic methods.